想让各位大神帮忙翻译下文章的摘要,翻译成英语的,万分感谢!【摘要】目的: 研究健脾活血方胃安散对胃癌前病变模型大鼠p53和p16基因表达的影响,以进一步探求其发病机制.方法 : 采用改进以
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![想让各位大神帮忙翻译下文章的摘要,翻译成英语的,万分感谢!【摘要】目的: 研究健脾活血方胃安散对胃癌前病变模型大鼠p53和p16基因表达的影响,以进一步探求其发病机制.方法 : 采用改进以](/uploads/image/z/12613289-41-9.jpg?t=%E6%83%B3%E8%AE%A9%E5%90%84%E4%BD%8D%E5%A4%A7%E7%A5%9E%E5%B8%AE%E5%BF%99%E7%BF%BB%E8%AF%91%E4%B8%8B%E6%96%87%E7%AB%A0%E7%9A%84%E6%91%98%E8%A6%81%2C%E7%BF%BB%E8%AF%91%E6%88%90%E8%8B%B1%E8%AF%AD%E7%9A%84%2C%E4%B8%87%E5%88%86%E6%84%9F%E8%B0%A2%21%E3%80%90%E6%91%98%E8%A6%81%E3%80%91%E7%9B%AE%E7%9A%84%3A+%E7%A0%94%E7%A9%B6%E5%81%A5%E8%84%BE%E6%B4%BB%E8%A1%80%E6%96%B9%E8%83%83%E5%AE%89%E6%95%A3%E5%AF%B9%E8%83%83%E7%99%8C%E5%89%8D%E7%97%85%E5%8F%98%E6%A8%A1%E5%9E%8B%E5%A4%A7%E9%BC%A0p53%E5%92%8Cp16%E5%9F%BA%E5%9B%A0%E8%A1%A8%E8%BE%BE%E7%9A%84%E5%BD%B1%E5%93%8D%2C%E4%BB%A5%E8%BF%9B%E4%B8%80%E6%AD%A5%E6%8E%A2%E6%B1%82%E5%85%B6%E5%8F%91%E7%97%85%E6%9C%BA%E5%88%B6.%E6%96%B9%E6%B3%95+%3A+%E9%87%87%E7%94%A8%E6%94%B9%E8%BF%9B%E4%BB%A5)
想让各位大神帮忙翻译下文章的摘要,翻译成英语的,万分感谢!【摘要】目的: 研究健脾活血方胃安散对胃癌前病变模型大鼠p53和p16基因表达的影响,以进一步探求其发病机制.方法 : 采用改进以
想让各位大神帮忙翻译下文章的摘要,翻译成英语的,万分感谢!
【摘要】目的: 研究健脾活血方胃安散对胃癌前病变模型大鼠p53和p16基因表达的影响,以进一步探求其发病机制.方法 : 采用改进以N-甲基-N’硝基-N-亚硝基胍(MNNG)为基础的联合造模方案造成胃癌前期病变大鼠模型,免疫组化方法观察胃粘膜p53、p16基因的表达.结果: p53免疫组化染色结果提示各组均为阴性表达;p16染色在表达率及表达强度方面,均有一定程度提高.其调节P16基因表达的作用与胃复春组比较具有显著性差异.结论:健脾活血方胃安散可提高抑癌基因p16表达,具有一定的预防胃癌前病变发展成胃癌的作用.
关键词:胃安散;胃癌前病变; p53;p16
想让各位大神帮忙翻译下文章的摘要,翻译成英语的,万分感谢!【摘要】目的: 研究健脾活血方胃安散对胃癌前病变模型大鼠p53和p16基因表达的影响,以进一步探求其发病机制.方法 : 采用改进以
Study of Jianpi Huoxue Decoction of Weiansan on gastric precancerous lesions in a rat model of p53 and p16 gene expression in the rat,in order to further explore its pathogenesis.Methods:using the improved to N- methyl -N ' nitro -N- nitrosoguanidine ( MNNG ) based combination modeling scheme resulted in precancerous lesions of gastric cancer in a rat model,immunohistochemical methods to observe the gastric mucosal p53,p16 gene expression.Results:p53 immunohistochemical staining results in each group were negative expression; p16 staining in the expression and the expression,has a certain degree enhance.The regulation of P16 gene expression and the role of Weifuchun group showed significant difference in comparison.Conclusion:strengthening spleen and Activating Blood Prescription of Weiansan can increase the expression of tumor suppressor gene p16,has certain prevention precancerous lesion developed into the role of gastric cancer.Key words:stomach powder; precancerous lesions of gastric cancer; p53; p16